cleanroom maintenance – Pharma GMP

Never Remove HEPA Filters Without Containment Measures in GMP Areas

digi — Tue, 30 Sep 2025 23:32:51 +0000

Never Remove HEPA Filters Without Containment Measures in GMP Areas Don’t Remove HEPA Filters Without Proper Containment Procedures Remember: Always use containment controls when replacing or removing HEPA filters — failure to do so compromises air quality and GMP compliance. Why This Matters in GMP High-Efficiency Particulate Air (HEPA) filters are critical components in HVAC...

Disinfect Drains in Wet Processing Areas on a Regular Schedule

digi — Thu, 21 Aug 2025 07:56:13 +0000

Disinfect Drains in Wet Processing Areas on a Regular Schedule Regularly Disinfect Drains in Wet Processing Zones to Prevent Contamination Remember: Always perform drain disinfection in wet processing areas on a defined schedule to prevent microbial buildup and GMP violations. Why This Matters in GMP Drains in wet processing zones — such as granulation, formulation,...

Ensure Each Drain Has Microbial Control Procedures in GMP Facilities

digi — Tue, 08 Jul 2025 13:01:25 +0000

Ensure Each Drain Has Microbial Control Procedures in GMP Facilities Implement Microbial Control Procedures for Every Drain in GMP Areas Remember: GMP requires all drains to be routinely cleaned, disinfected, and monitored to prevent microbial growth and environmental contamination. Why This Matters in GMP Drains are common breeding grounds for bacteria, fungi, and biofilms in...

Never Apply Pressure to HEPA Filters During Cleaning in GMP Facilities

digi — Sat, 31 May 2025 00:47:16 +0000

Never Apply Pressure to HEPA Filters During Cleaning in GMP Facilities Never Apply Pressure to HEPA Filters During Cleaning Activities Remember: Applying pressure or physical contact with HEPA filters damages them and undermines GMP cleanroom contamination control. Why This Matters in GMP HEPA filters are critical in maintaining cleanroom classifications by removing 99.97% of particles...