facility maintenance – Pharma GMP

Alert QA Before Flushing Drain Systems to Avoid GMP Compliance Issues

digi — Wed, 16 Jul 2025 14:36:01 +0000

Alert QA Before Flushing Drain Systems to Avoid GMP Compliance Issues Never Flush Drain Systems Without Prior QA Notification in GMP Areas Remember: GMP mandates that flushing of drains and wastewater systems must be pre-approved by QA to prevent contamination risks and ensure traceability. Why This Matters in GMP Flushing drain systems is a necessary...

Use Passivation Methods to Maintain Stainless Steel Equipment Integrity

digi — Tue, 17 Jun 2025 01:36:22 +0000

Use Passivation Methods to Maintain Stainless Steel Equipment Integrity Passivate Stainless Steel Equipment to Ensure Cleanability and Longevity Remember: GMP-grade stainless steel equipment must undergo regular passivation to maintain corrosion resistance and prevent contamination risks. Why This Matters in GMP Stainless steel is widely used in pharmaceutical equipment due to its non-reactivity and cleanability. However,...

Avoid Water Stagnation in GMP Drains and Sinks to Prevent Contamination

digi — Fri, 13 Jun 2025 08:23:45 +0000

Avoid Water Stagnation in GMP Drains and Sinks to Prevent Contamination Prevent Water Stagnation in Drains and Sinks to Avoid Microbial Risk Remember: Water stagnation in GMP areas is a major source of microbial growth—ensure drains and sinks are regularly inspected, cleaned, and dried. Why This Matters in GMP Standing water is a fertile breeding...

Do Not Allow Flaking Paint in GMP Controlled Manufacturing Environments

digi — Fri, 06 Jun 2025 01:51:12 +0000

Do Not Allow Flaking Paint in GMP Controlled Manufacturing Environments Flaking Paint Must Be Eliminated from GMP Controlled Areas Remember: Peeling paint is an unacceptable contamination source in GMP areas—facilities must be maintained to prevent such physical degradation. Why This Matters in GMP Facility walls and ceilings must be constructed and maintained to minimize particle...