Granulation Deviations: Lumps, Over-Wet Mass and Poor Flow

digi — Tue, 25 Nov 2025 15:36:04 +0000

Granulation Deviations: Lumps, Over-Wet Mass and Poor Flow Step-by-Step Tutorial on Managing Granulation Process Controls in Tablet Manufacturing The granulation step is a critical phase in tablet manufacturing that directly influences the final product’s quality attributes, including content uniformity, compressibility, and dissolution. However, deviations such as lumps in the granulate, over-wet or under-mixed granules, and...

flow – Pharma GMP

Granulation Deviations: Lumps, Over-Wet Mass and Poor Flow